A REVIEW OF SODIUM PENTOBARBITAL (NAP)

Contraindicated (1)pentobarbital will decrease the extent or effect of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers can lead to lowered serum concentrations and lack of antimalarial efficacypentobarbital will lower the level or effect of eltrombopag by impacting